
Trilipiderm
Trilipiderm DermiGuard Gel Crème, 1.7 fl. oz
- Lightweight gel crème provides soothing, weightless hydration
- Balances the skin microbiome and fortifies the barrier
- Reduces the appearance of fine lines and wrinkles
- Protects against environmental stressors and irritation
- Perfect for spas, dermatology clinics, and professional skincare use
- Made in the USA
Dermiguard Gel Crème | Microbiome-Balancing Hydrating Moisturizer
Dermiguard Gel Crème is a lightweight, age-defying moisturizer that delivers long-lasting hydration while restoring skin balance and comfort. Designed to calm redness and support the skin’s natural defenses, this advanced formula features postbiotics, ceramides, peptides, and powerful antioxidants. Ideal for all skin types—including sensitive, oily, and combination—it leaves skin looking firm, smooth, and refreshed.
Rebalancing Moisturizer | Professional-Grade Barrier Support & Hydration
This dermatologist-formulated gel crème helps reinforce the skin barrier, reduce the appearance of fine lines, and restore youthful tone and texture. With a fast-absorbing, non-greasy finish, it protects against environmental aggressors while delivering visible anti-aging benefits. Perfect for daily use in high-end spas, dermatology practices, and wellness centers.
Why You’ll Love It:
- Supports a Healthy Microbiome: A postbiotic blend with vitamins, minerals, and calcium restores balance and reduces redness
- Repairs & Protects the Skin Barrier: Ceramide NP mimics natural lipids to lock in hydration and defend against moisture loss
- Firms & Smooths Skin: Palmitoyl Tripeptide-38 helps reduce the appearance of wrinkles and supports healthy collagen
- Environmental Defense: Ergothioneine, a powerhouse antioxidant, protects against oxidative stress and visible aging
- Weightless Hydration: Absorbs quickly without clogging pores—ideal for daily use under SPF and makeup
Key Benefits:
- Replenishes moisture and improves skin texture
- Reduces the appearance of fine lines and wrinkles
- Fortifies and repairs the skin’s protective barrier
- Balances skin’s natural microbiome for a healthy complexion
- Lightweight, non-comedogenic formula perfect for sensitive or acne-prone skin
- Dermatologist-formulated and safe for twice-daily use
How to Use:
After treatment serum, apply to the face and neck twice daily. Follow with SPF
in the morning.
Ideal For:
- Normal, oily, dry, sensitive, and combination skin
- Skin prone to redness, dehydration, or barrier disruption
- Use in medical spas, dermatology clinics, or as part of a professional-grade skincare regimen
Key Ingredients:
- Postbiotic Complex – Nourishes and balances the skin microbiome for reduced redness and irritation
- Ceramide NP – Strengthens and hydrates by mimicking natural ceramides
- Palmitoyl Tripeptide-38 – Anti-aging peptide that firms, smooths, and improves elasticity
- Ergothioneine – Superior antioxidant that outperforms CoQ10, Vitamin C, and Vitamin E
- Squalane & Hyaluronic Acid – Deliver lasting moisture without heaviness
Product Highlights:
- Balances and supports a healthy skin microbiome
- Delivers lightweight hydration for a smooth, comfortable feel
- Clinically proven peptides improve firmness and reduce wrinkles
- Ceramides restore barrier function and lock in moisture
- Ergothioneine and postbiotics defend against environmental damage
- Ideal for all skin types, including oily and sensitive skin
Skin Type: | All skin types, including oily, sensitive, and mature skin |
Texture: | Weightless gel crème |
ingredients: |
Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Propanediol, Squalane, Cetearyl Alcohol, Ceramide Np, Cocos Nucifera (Coconut) Fruit Extract, Palmitoyl Tripeptide-38, Ergothioneine, Sodium Hyaluronate, Lactobacillus Ferment, Sodium Stearoyl Glutamate, Carbomer, Sodium Polyacrylate, Diisostearyl Malate, Hexylene Glycol, Sodium Phytate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Hydroxide, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin. |
Made In: | USA |
- Lightweight gel crème provides soothing, weightless hydration
- Balances the skin microbiome and fortifies the barrier
- Reduces the appearance of fine lines and wrinkles
- Protects against environmental stressors and irritation
- Perfect for spas, dermatology clinics, and professional skincare use
- Made in the USA
Dermiguard Gel Crème | Microbiome-Balancing Hydrating Moisturizer
Dermiguard Gel Crème is a lightweight, age-defying moisturizer that delivers long-lasting hydration while restoring skin balance and comfort. Designed to calm redness and support the skin’s natural defenses, this advanced formula features postbiotics, ceramides, peptides, and powerful antioxidants. Ideal for all skin types—including sensitive, oily, and combination—it leaves skin looking firm, smooth, and refreshed.
Rebalancing Moisturizer | Professional-Grade Barrier Support & Hydration
This dermatologist-formulated gel crème helps reinforce the skin barrier, reduce the appearance of fine lines, and restore youthful tone and texture. With a fast-absorbing, non-greasy finish, it protects against environmental aggressors while delivering visible anti-aging benefits. Perfect for daily use in high-end spas, dermatology practices, and wellness centers.
Why You’ll Love It:
- Supports a Healthy Microbiome: A postbiotic blend with vitamins, minerals, and calcium restores balance and reduces redness
- Repairs & Protects the Skin Barrier: Ceramide NP mimics natural lipids to lock in hydration and defend against moisture loss
- Firms & Smooths Skin: Palmitoyl Tripeptide-38 helps reduce the appearance of wrinkles and supports healthy collagen
- Environmental Defense: Ergothioneine, a powerhouse antioxidant, protects against oxidative stress and visible aging
- Weightless Hydration: Absorbs quickly without clogging pores—ideal for daily use under SPF and makeup
Key Benefits:
- Replenishes moisture and improves skin texture
- Reduces the appearance of fine lines and wrinkles
- Fortifies and repairs the skin’s protective barrier
- Balances skin’s natural microbiome for a healthy complexion
- Lightweight, non-comedogenic formula perfect for sensitive or acne-prone skin
- Dermatologist-formulated and safe for twice-daily use
How to Use:
After treatment serum, apply to the face and neck twice daily. Follow with SPF
in the morning.
Ideal For:
- Normal, oily, dry, sensitive, and combination skin
- Skin prone to redness, dehydration, or barrier disruption
- Use in medical spas, dermatology clinics, or as part of a professional-grade skincare regimen
Key Ingredients:
- Postbiotic Complex – Nourishes and balances the skin microbiome for reduced redness and irritation
- Ceramide NP – Strengthens and hydrates by mimicking natural ceramides
- Palmitoyl Tripeptide-38 – Anti-aging peptide that firms, smooths, and improves elasticity
- Ergothioneine – Superior antioxidant that outperforms CoQ10, Vitamin C, and Vitamin E
- Squalane & Hyaluronic Acid – Deliver lasting moisture without heaviness
Product Highlights:
- Balances and supports a healthy skin microbiome
- Delivers lightweight hydration for a smooth, comfortable feel
- Clinically proven peptides improve firmness and reduce wrinkles
- Ceramides restore barrier function and lock in moisture
- Ergothioneine and postbiotics defend against environmental damage
- Ideal for all skin types, including oily and sensitive skin
Skin Type: | All skin types, including oily, sensitive, and mature skin |
Texture: | Weightless gel crème |
ingredients: |
Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Propanediol, Squalane, Cetearyl Alcohol, Ceramide Np, Cocos Nucifera (Coconut) Fruit Extract, Palmitoyl Tripeptide-38, Ergothioneine, Sodium Hyaluronate, Lactobacillus Ferment, Sodium Stearoyl Glutamate, Carbomer, Sodium Polyacrylate, Diisostearyl Malate, Hexylene Glycol, Sodium Phytate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Hydroxide, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin. |
Made In: | USA |

Trilipiderm DermiGuard Gel Crème, 1.7 fl. oz






- Lightweight gel crème provides soothing, weightless hydration
- Balances the skin microbiome and fortifies the barrier
- Reduces the appearance of fine lines and wrinkles
- Protects against environmental stressors and irritation
- Perfect for spas, dermatology clinics, and professional skincare use
- Made in the USA
Dermiguard Gel Crème | Microbiome-Balancing Hydrating Moisturizer
Dermiguard Gel Crème is a lightweight, age-defying moisturizer that delivers long-lasting hydration while restoring skin balance and comfort. Designed to calm redness and support the skin’s natural defenses, this advanced formula features postbiotics, ceramides, peptides, and powerful antioxidants. Ideal for all skin types—including sensitive, oily, and combination—it leaves skin looking firm, smooth, and refreshed.
Rebalancing Moisturizer | Professional-Grade Barrier Support & Hydration
This dermatologist-formulated gel crème helps reinforce the skin barrier, reduce the appearance of fine lines, and restore youthful tone and texture. With a fast-absorbing, non-greasy finish, it protects against environmental aggressors while delivering visible anti-aging benefits. Perfect for daily use in high-end spas, dermatology practices, and wellness centers.
Why You’ll Love It:
- Supports a Healthy Microbiome: A postbiotic blend with vitamins, minerals, and calcium restores balance and reduces redness
- Repairs & Protects the Skin Barrier: Ceramide NP mimics natural lipids to lock in hydration and defend against moisture loss
- Firms & Smooths Skin: Palmitoyl Tripeptide-38 helps reduce the appearance of wrinkles and supports healthy collagen
- Environmental Defense: Ergothioneine, a powerhouse antioxidant, protects against oxidative stress and visible aging
- Weightless Hydration: Absorbs quickly without clogging pores—ideal for daily use under SPF and makeup
Key Benefits:
- Replenishes moisture and improves skin texture
- Reduces the appearance of fine lines and wrinkles
- Fortifies and repairs the skin’s protective barrier
- Balances skin’s natural microbiome for a healthy complexion
- Lightweight, non-comedogenic formula perfect for sensitive or acne-prone skin
- Dermatologist-formulated and safe for twice-daily use
How to Use:
After treatment serum, apply to the face and neck twice daily. Follow with SPF
in the morning.
Ideal For:
- Normal, oily, dry, sensitive, and combination skin
- Skin prone to redness, dehydration, or barrier disruption
- Use in medical spas, dermatology clinics, or as part of a professional-grade skincare regimen
Key Ingredients:
- Postbiotic Complex – Nourishes and balances the skin microbiome for reduced redness and irritation
- Ceramide NP – Strengthens and hydrates by mimicking natural ceramides
- Palmitoyl Tripeptide-38 – Anti-aging peptide that firms, smooths, and improves elasticity
- Ergothioneine – Superior antioxidant that outperforms CoQ10, Vitamin C, and Vitamin E
- Squalane & Hyaluronic Acid – Deliver lasting moisture without heaviness
Product Highlights:
- Balances and supports a healthy skin microbiome
- Delivers lightweight hydration for a smooth, comfortable feel
- Clinically proven peptides improve firmness and reduce wrinkles
- Ceramides restore barrier function and lock in moisture
- Ergothioneine and postbiotics defend against environmental damage
- Ideal for all skin types, including oily and sensitive skin
Skin Type: | All skin types, including oily, sensitive, and mature skin |
Texture: | Weightless gel crème |
ingredients: |
Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Propanediol, Squalane, Cetearyl Alcohol, Ceramide Np, Cocos Nucifera (Coconut) Fruit Extract, Palmitoyl Tripeptide-38, Ergothioneine, Sodium Hyaluronate, Lactobacillus Ferment, Sodium Stearoyl Glutamate, Carbomer, Sodium Polyacrylate, Diisostearyl Malate, Hexylene Glycol, Sodium Phytate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Hydroxide, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin. |
Made In: | USA |
Manufacturer Warranty: 1 year